UPDATE 11.15.09: Turns out the N. Penn store no longer exists. Mikeg left a comment below explaining the fate of that store...
"This is not the North Penn Acme. This was built after the ad, when the Wyoming Valley Mall was built, probably 1971 or 1972. The North Penn Ave . Acme was close to Downtown Wilkes-Barre, just a few blocks from the Penn Plaza store. It was my Aunt and Grandmother's favorite Acme to shop in for some reason. The building burned down shortly after the ad was in the paper, probably late 1969 or early 1970. Of course, since it was so near the Penn Plaza and Rt. 309 stores, it was not rebuilt. It was the yellow tile front "neighborhood" Acme."
Since the N. Penn store is gone, I will leave this Wyoming Valley Mall Acme in it's place.
Images above courtesy of Wyoming Valley Blog